WebCommon domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. Web2 okt. 2024 · Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and …
KEGG PATHWAY: ko03008 - Genome
Web1 dag geleden · Reporter cargos were engineered to fuse a nuclear export sequence (NES) with sequences of simian virus 40 T antigen (NLS) or cap-binding protein 80 (2xNLS), which bind to Imp-α/β heterodimers ... Web17 aug. 2024 · Im Cytoplasma befindliche Transportrezeptoren erkennen die Signalstrukturen der für den Zellkern bestimmten Proteine. Import und Export von Proteinen werden über eine Reihe von Transportrezeptoren, ... (ras-related nuclear protein) und weiterer Faktoren, z.B. vom nucleären Transportfaktor 2 (NTF2), vollzogen. duty holder advice note
HMDB0001273 (Guanosine triphosphate) Protein Associations
Web8 jan. 2001 · We recently reported the identification of NXT1, an NTF2-related export factor that stimulates nuclear protein export in permeabilized cells and undergoes nucleocytoplasmic shuttling in vivo (Black, B.E., L. Lévesque, J.M. Holaska, T.C. Wood, and B.M. Paschal. 1999. Web83454 Ensembl ENSG00000269405 ENSMUSG00000009941 UniProt Q9GZY0 n/a RefSeq (mRNA) NM_022053 NM_001039910 NM_017809 NM_001289735 NM_001289736 NM_031259 RefSeq (protein) NP_071336 NP_001093156 n/a Location (UCSC) Chr X: 102.25 – 102.33 Mb Chr X: 133.85 – 133.87 Mb PubMed search Wikidata View/Edit … Web17 nov. 2014 · The NXF1:NXT1 complex (also known as TAP:p15) is a general mRNA nuclear export factor that is conserved from yeast to humans. NXF1 is a modular protein constructed from four domains (RRM, LRR, NTF2-like and UBA domains). It is currently unclear how NXF1:NXT1 binds transcripts and whether there is higher organization of … duty from us to canada