Mtor cst 2983
Web10 apr. 2024 · Background Uveal melanoma (UM) is the most common intraocular malignancy in adults, with a poor survival prognosis. To date, limited understanding of UM’s molecular mechanisms constitutes an obstacle to developing effective therapy. In this study, we examined key regulators mediating UM progression and their clinical relevance. … Web2 mar. 2024 · BMECs (bEnd.3 or HBMEC) with 3 × 10 7 cells were lysed in 500 μL co-IP buffer (Beyotime Biotechnology), and incubated with 5 μg of mTOR (CST, 2983) or E2F1 …
Mtor cst 2983
Did you know?
WebAfter mTOR activation, mTORC1 (rapamycin-sensitive mTOR complex 1) initiates the phosphorylation of p70S6K and 4EBP1 (Ponticelli 2004). This signaling cascade effect …
Web8 iul. 2024 · Introduction. Skeletal muscle occupies∼40% of the mammalian body and is essential for maintaining posture, locomotion, blood circulation, breathing, and … WebCell Signaling Technology's Phospho-mTOR (Ser2448) (D9C2) XP ® Rabbit mAb is a Rabbit monoclonal antibody. The Phospho-mTOR (Ser2448) (D9C2) XP ® Rabbit mAb Antibody was generated using MTOR as the antigen. It reacts with Human, Mouse, Rat, and Non-Human Primate. This antibody has been shown to work in applications such as: …
Web29 sept. 2024 · Fascaplysin has been reported to exert anti-cancer effects by inhibiting cyclin-dependent kinase 4 (CDK4); however, the precise mode of action by which … WebGBM cells. Lovastatin triggered autophagy initiation possibly by inhibiting the Akt/mTOR signaling pathway. Moreover, lovastatin might impair the autophagosome-lysosome fusion machinery by suppressing LAMP2 and dynein. ese results suggested that lovastatin could enhance the chemotherapy efficacy of TMZ in treating GBM cells. e mechanism may be
Web31 aug. 2024 · a, b Western blot analysis of AKT, p-AKT, FOXO1, p-FOXO1, mTOR and p-mTOR on different groups of ECs treated with DMSO or rapamycin. c, d Expression of FOXO1 in the nucleus was detected by western blot. e NC-ECs, TIE2-WT-ECs and TIE2-L914F-ECs were subjected to IF staining with anti-FOXO1 antibody after the RAPA (15 …
Web(19) Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway Journal of Experimental & Clinical Cancer Research December 1, 2024 Yang Yang et al. (CST, 2535), mTOR (CST, 2983), p-mTOR (CST,5536), p … dsc logistics schedulingWeb3 sept. 2024 · Cell Signaling Technology mTOR antibody (CST, 5536) was used in western blot on mouse samples at 1:1000 (fig 6d). J Exp Clin Cancer Res (2024) ncbi: domestic … ds cloud下载Webits antitumor effects. Methods To explore the use of apoptin in tumor gene therapy, a recombinant adenovirus ATV expressing the apoptin protein was assessed to determine its lethal and growth-inhibitory effects on human cervical cancer cell line (HeLa) cells in vitro. Nonapoptotic autophagy of HeLa cells infected with ATV was assessed by examining the … commercial general liability in ohioWebgastric adenoma in mice. Mechanistically, c-Myc promoted tumorigenesis through the AKT/ mammalian target of rapamycin (mTOR) path-way. Furthermore, AKT inhibitor (MK … commercial general contractors suwanee gaWebCitations: (>1k) Cell Signaling Technology's mTOR (7C10) Rabbit mAb is a Rabbit monoclonal antibody. The mTOR (7C10) Rabbit mAb Antibody was generated using … commercial general liability claims madeWeb4 aug. 2015 · The issue of whether ERK activation determines matrix synthesis or degradation in osteoarthritis (OA) pathogenesis currently remains controversial. Our … commercial general contractors richmond vaWebWestern blot was developed using anti-mTOR (2983, CST), anti-p-mTOR (2974, CST), anti-4EBP1 (9644, CST), anti-p-4EBP1 (2855, CST), anti-β-actin (47,778, SantaCruz), mouse … dsc logs on windows