Incidence of thrombocytopenia with daptomycin
WebOct 1, 2012 · Although the incidence is low, more than 100 drugs have been implicated in thrombocytopenia, including quinine, sulfonamides, abciximab, carbamazepine, and vancomycin, as well as herbal remedies ... WebMany medications can induce antibodies that cause thrombocytopenia. 1,2 Neutropenia is a well-recognized complication of therapy with vancomycin, a glycopeptide antibiotic widely used for the...
Incidence of thrombocytopenia with daptomycin
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WebOct 28, 2024 · In 2 recent studies, the prevalence of thrombocytopenia was highly variable, as it ranged from 6% to 24%. 4, 5 Furthermore, follow‐up data about the relationship between thrombocytopenia and mortality in patients with AF were not reported. WebFirst, the time from daptomycin initiation to the diagnosis of thrombocytopenia was 4 days. Drug-dependent antiplatelet antibodies usually develop only after 1 to 2 weeks of drug exposure ( 1 ). However, the rapid drop in the patient's platelet count strongly suggests immune-mediated thrombocytopenia.
WebJun 1, 2024 · Drug-induced thrombocytopenia secondary to antibiotic exposure is a rare complication more commonly associated with other medications. In this review, we … WebOct 1, 2012 · described case of daptomycin-induced thrombocytopenia. W e report a case of daptomycin-induced immune thrombo- cytopenia observed in a 64-year-old man admitted …
WebApr 12, 2024 · Immune thrombocytopenia (ITP) is the consequence of a complex, still not completely understood immunological dysregulation. Proposed mechanisms include autoantibody-induced platelet destruction, impaired platelet production as well as abnormalities in T-cell immunity, such as Th1 polarization, a high proportion of Th17 cells … WebJun 1, 2024 · In the subset of studies focusing on high-dose daptomycin, patients receiving daptomycin tended to show a higher clinical response rate (OR 1.61; 95% CI 0.37–7.09; I2 …
WebJul 5, 2024 · Drug-induced non-immune thrombocytopenia. Drugs like valproic acid, daptomycin, linezolid cause thrombocytopenia by dose-dependent suppression of platelet production. Infections: Viral: HIV, hepatitis C, Ebstein-Barr virus, parvovirus, mumps, varicella, rubella, Zika viral infections can cause thrombocytopenia.
WebJun 15, 2006 · The use of daptomycin has been associated with an elevation in creatine phosphokinase level, with a reported incidence of 2.8% in phase III clinical trials. Published case reports have documented the presence of myopathy in patients who received daptomycin; however, there have been no previously reported cases of rhabdomyolysis in … cereal for 8 month babyWebOct 21, 2024 · Citation 148 Weigelt et al found the incidence of reported thrombocytopenia (level not defined) was statistically more common in 592 patients receiving linezolid ... and vancomycin were USD $18,057, $20,698, and $23,671, respectively. The cost-effectiveness ratios for linezolid, daptomycin, and vancomycin were calculated to be $37,604, $44,086 ... cereal for dinner weight lossWebNov 30, 2024 · Thrombocytopenia can occur in 10% to 30% of patients treated with heparin in the absence of an obvious involvement of the immune system. The underlying pathophysiology is thought to be mediated by direct binding of heparin to platelets, resulting in mild platelet activation. cereal for girlsWebHeparin-induced thrombocytopenia (HIT) is a hypersensitivity reaction to unfractionated heparin and low molecular weight heparin mediated by an IgG antibody. 29 One study found that the risk of HIT with low molecular … cereal for breakfast cornWebThrombocytopaenia, but not neutropaenia, is described as a possible or probable adverse effect in the product information. Up to now, two case reports of daptomycin-induced … buy season 3 shopkinsWebThe reported incidence of drug-induced thrombocytopenia (DIT) is 10 cases per 1 million people per year, but the number is presumed to be higher because of underreporting and … buy season 3 of the pretenderWebNov 23, 2024 · Common side effects of daptomycin may include: chest pain, trouble breathing; headache, dizziness; stomach pain, vomiting; swelling; abnormal liver function tests; rash, itching, sweating; trouble sleeping; sore throat; or increased blood pressure. This is not a complete list of side effects and others may occur. cereal for gingerbread house roof